I strongly recommend, as a Road Warrior, to plan trips for pleasure and ONLY pleasure. Why? Well, let's look at the flip side.
The Business Trip:Some times you can be in a city for a few hours, a day, maybe a week. During that time you usually work, maybe go into a satellite office, or just go from meeting to meeting. Most companies don't want you there longer than necessary so you don't have any fun really. This is why I recommending taking as many "moments" as possible on these business trips.
-In you taxi, look up at the buildings and around! Don't stare at your blackberry the entire time.
-When you're done for the day, try to see or do one thing you couldn't anywhere else.
-Keep track of the places you eat and buildings you go to. On your next time, try to venture out.
Doing it little by little each trip relaxes you enough, without stressing out your boss or your wallet.
The Pleasure Trip:
This is even more important if you aren't able to schedule your little moments on business trips. Even though you are seeing the world, you aren't usually enjoying it. This in turn, makes every trip a chore and a routine part of your job. By ensuring yourself a pleasure trip, there is a little break in the monotony and re-excites you to go somewhere. On these trips, do not do any work.
-Keep your phone off, especially during dinner, family times, or for romantic occasions.
-Do your best to not talk about work. I think they will last without you.
-Keep emailing to an absolute minimum or none if possible.
-Take the time to think about you and your loved ones.
Whether you like it or not, if you are a serious worker it will come out in conversation, but keep that to a minimum. The only except to the rule is networking because you never know if there is a good opportunity, but if the bell boy asks why you can afford such nice luggage...you don't need to give a pitch.
I went to the Oregon Coast for my last Pleasure Trip and was able to mix business with pleasure on my trip to Utah and Idaho. You only need a day or two to rejuvenate you to keep going and sometimes you just need a moment.